Endocrine Abstracts

IntroductionLangerhans cell histiocytosis (LCH) is a rare monoclonal disease characterized by abnormal proliferation and accumulation of bone marrow-derived Langerhans cells in various tissues. Heterogeneous collections of Langerhans cells with neutrophils, lymphocytes, eosinophils, histiocytes and Birbeck granules are observed in biopsy materials. Endocrinologic features of LCH are usually due to posterior pituitary involvement. Thyroid infiltration is ...